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Publikationen

2017                    2016                     2015                     2014                      2013                     2012                     2011                     2010    
Publikationen 2017

Alt V. Antimicrobial coated implants in trauma and orthopaedics-A clinical review and risk-benefit analysis. Injury 2017 Mar;48(3):599-607. doi: 10.1016/j.injury.2016.12.011. Epub 2016 Dec 21

Alt V, Simpson H, Miclau T. Intramedullary nailing-Evolution of treatment. Injury 2017 Jun;48 Suppl 1:S1-S2

Bungartz M, Kunisch E, Maenz S, Horbert V, Xin L, Gunnella F, Mika J, Borowski J, Bischoff S, Schubert H, Sachse A, Illerhaus B, Günster J, Bossert J, Jandt KD, Plöger F, Kinne RW, Brinkmann O. GDF5 significantly augments the bone formation induced by an injectable, PLGA-fiber reinforced, brushite-forming cement in a sheep defect model of lumbar osteopenia. Spine J 2017 Jun 19. pii: S1529-9430(17)30269-3. doi: 10.1016/j.spinee.2017.06.007. [Epub ahead of print]

Daghma DES, Malhan D, Simon P, Stötzel S, Kern S, Hassan F, Lips KS, Heiss C, El Khassawna T. Computational segmentation of collagen fibers in bone matrix indicates bone quality in ovariectomized rat spine. J Bone Miner Metab 2017 Jun 6. doi: 10.1007/s00774-017-0844-5. [Epub ahead of print]

El Khassawna T, Daghma DES, Stoetzel S, Ray S, Kern S, Malhan D, Alt V, Thormann U, Henß A, Rohnke M, Stengel A, Hassan F, Maenz S, Jandt KD, Diefenbeck M, Schumacher M, Gelinsky M, Lips KS, Heiss C. Postembedding Decalcification of Mineralized Tissue Sections Preserves the Integrity of Implanted Biomaterials and Minimizes Number of Experimental Animals. Biomed Res Int 2017;2017:2023853. doi: 10.1155/2017/2023853. Epub 2017 Mar 23

El Khassawna T, Merboth F, Malhan D, Böcker W, Daghma DES, Stoetzel S, Kern S, Hassan F, Rosenbaum D, Langenstein J, Bauer N, Schlagenhauf A, Rösen-Wolff A, Schulze F, Rupp M, Hose D, Secklinger A, Ignatius A, Wilke HJ, Lips KS, Heiss C. Osteocyte Regulation of Receptor Activator of NF-κB Ligand/Osteoprotegerin in a Sheep Model of Osteoporosis. Am J Pathol 2017 Jun 12. pii: S0002-9440(17)30132-3. doi: 10.1016/j.ajpath.2017.04.005. [Epub ahead of print]

El Khassawna T, Serra A, Bucher CH, Petersen A, Schlundt C, Könnecke I, Malhan D, Wendler S, Schell H, Volk HD, Schmidt-Bleek K, Duda GN. T Lymphocytes Influence the Mineralization Process of Bone. Front Immunol 2017 May 24;8:562. doi: 10.3389/fimmu.2017.00562. eCollection 2017

Gunnella F, Kunisch E, Bungartz M, Maenz S, Horbert V, Xin L, Mika J, Borowski J, Bischoff S, Schubert H, Hortschansky P, Sachse A, Illerhaus B, Günster J, Bossert J, Jandt KD, Plöger F, Kinne RW, Brinkmann O. Low-dose BMP-2 is sufficient to enhance the bone formation induced by an injectable, PLGA-fiber reinforced, brushite-forming cement in a sheep defect model of lumbar osteopenia. Spine J 2017 Jun 12. pii: S1529-9430(17)30267-X. doi: 10.1016/j.spinee.2017.06.005. [Epub ahead of print]

Gunnella F, Kunisch E, Maenz S, Horbert V, Xin L, Mika J, Borowski J, Bischoff S, Schubert H, Sachse A, Illerhaus B, Günster J, Bossert J, Jandt KD, Plöger F, Kinne RW, Brinkmann O, Bungartz M. The GDF5 mutant BB-1 enhances the bone formation induced by an injectable, PLGA-fiber reinforced, brushite-forming cement in a sheep defect model of lumbar osteopenia. Spine J 2017 Oct 12. pii: S1529-9430(17)31051-3. doi: 10.1016/j.spinee.2017.10.002. [Epub ahead of print]

Heiss C, Kern S, Malhan D, Böcker W, Engelhardt M, Daghma DES, Stoetzel S, Schmitt J, Ivo M, Kauschke V, Lips KS, Tushtev K, Rezwan K, El Khassawna T. A New Clinically Relevant T-Score Standard to Interpret Bone Status in a Sheep Model. Med Sci Monit Basic Res 2017 Oct 2;23:326-335

Hess U, Shahabi S, Treccani L, Streckbein P, Heiss C, Rezwan K. Co-delivery of cisplatin and doxorubicin from calcium phosphate beads/matrix scaffolds for osteosarcoma therapy. Mater Sci Eng C Mater Biol Appl 2017 Aug 1;77:427-435. doi: 10.1016/j.msec.2017.03.164. Epub 2017 Mar 21

Horbert V, Lange M, Reuter T, Hoffmann M, Bischoff S, Borowski J, Schubert H, Driesch D, Mika J, Hurschler C, Kinne RW. Comparison of Near-Infrared Spectroscopy with Needle Indentation and Histology for the Determination of Cartilage Thickness in the Large Animal Model Sheep. Cartilage 2017 Oct 1:1947603517731851. doi: 10.1177/1947603517731851. [Epub ahead of print]

Lykhmus O, Voytenko LP, Lips KS, Bergen I, Krasteva-Christ G, Vetter DE, Kummer W, Skok M. Nicotinic Acetylcholine Receptor α9 and α10 Subunits Are Expressed in the Brain of Mice. Front Cell Neurosci 2017 Sept 12. doi: 10.3389/fncel.2017.00282

Mika J, Clanton TO, Ambrose CG, Kinne RW. Surgical preparation for articular cartilage regeneration in the osteoarthritic knee joint. Cartilage 2017 Oct;8(4):365-368. doi: 10.1177/1947603516670710. Epub 2016 Sep 28

Petzold R, Vehlow D, Urban B, Grab AL, Cavalcanti-Adam EA, Alt V, Müller M. Colloid, adhesive and release properties of nanoparticular ternary complexes between cationic and anionic polysaccharides and basic proteins like bone morphogenetic protein BMP-2. Colloids Surf B Biointerfaces 2017 Mar 1;151:58-67

Ray S, Khassawna TE, Sommer U, Thormann U, Wijekoon ND, Lips K, Heiss C, Alt V. Differences in expression of Wnt antagonist Dkk1 in healthy versus pathological bone samples. J Microsc 2017 Jan;265(1):111-120. doi: 10.1111/jmi.12469. Epub 2016 Aug 31

Rohnke M, Pfitzenreuter S, Mogwitz B, Henß A, Thomas J, Bieberstein D, Gemming T, Otto SK, Ray S, Schumacher M, Gelinsky M, Alt V. Strontium release from Sr2+-loaded bone cements and dispersion in healthy and osteoporotic rat bone. J Control Release 2017 Jul 27;262:159-169

Schäfer C, Tilp S, Oltenau C, Szalay G, Heiß C. Operative Möglichkeiten zur Behandlung von fehlverheilten distalen Unterarmfrakturen im Kindesalter. Trauma Berufskrankh 2017;19 (Suppl 2):S135-S139. doi: 10.1007/s10039-017-0245-y

Schleicher I, van der Mei SH, Mika J, Kreuder JG. Chirurgisches Aufklärungsgespräch in der studentischen Lehre.[Teaching medical students informed consent]. Unfallchirurg 2017 Jan 12. doi: 10.1007/s00113-016-0298-6. [Epub ahead of print] German

Schneck E, Koch C, Borgards M, Reichert M, Hecker A, Heiß C, Padberg W, Alejandre-Lafont E, Röhrig R, Krombach GA, Weigand M, Bernhard M, Roller FC. Impact of Abdominal Follow-Up Sonography in Trauma Patients Without Abdominal Parenchymal Organ Lesion or Free Intraabdominal Fluid in Whole-Body Computed Tomography. RöFo 2017 Feb;189(2):128-136. doi: 10.1055/s-0042-120844. Epub 2017 Jan 31

Schumacher TC, Tushtev K, Wagner U, Becker C, Große Holthaus M, Hein SB, Haack J, Heiss C, Engelhardt M, El Khassawna T, Rezwan K. A novel, hydroxyapatite-based screw-like device for anterior cruciate ligament (ACL) reconstructions. Knee 2017 Jul 22; pii: S0968-0160(17)30188-6. doi: 10.1016/j.knee.2017.07.005. [Epub ahead of print]

Publikationen 2016

Alt V, Cheung WH, Chow SK, Thormann U, Cheung EN, Lips KS, Schnettler R, Leung KS. Bone formation and degradation behavior of nanocrystalline hydroxyapatite with or without collagen-type 1 in osteoporotic bone defects - an experimental study in osteoporotic goats. Injury 2016 Jun;47 Suppl 2:S58-65

Alt V, Miclau T. Osteoporotic fractures - the biological perspective. Injury 2016 Jan;47 Suppl 1:S1-2

Augat P, Robioneck PB, Abdulazim A, Wipf F, Lips KS, Alt V, Schnettler R, Heiss C. Fixation performance of an ultrasonically fused, bioresorbable osteosynthesis implant: A biomechanical and biocompatibility study. J Biomed Mater Res B Appl Biomater 2016; 104(1):170-9

Beckmann J, Dittmann N, Schütz I, Klein J, Lips KS. Effect of M3 muscarinic acetylcholine receptor deficiency on collagen antibody-induced arthritis. Arthritis Res Ther 2016 Jan 19;18:17

Biehl C, Eckhard M, Szalay G, Heiss C. Minor-Amputationen beim diabetischen Fußsyndrom. Oper Orthop Traumatol 2016 Oct;28(5):365-72

Biehl C, Thormann U, Heiß C.  Komplikationen in der Kniechirurgie des Rheumatikers. Akt Rheumatol 2016, DOI: 10.1055/s-0042-108724

Biehl C, Thormann U, Madera N, Heiß C. Joint Involvement in Ochronosis. Surgery Curr Res 2016;6: 279

Bungartz M, Maenz S, Kunisch E, Horbert V, Xin L, Gunnella F, Mika J, Borowski J, Bischoff S, Schubert H, Sachse A, Illerhaus B, Günster J, Bossert J, Jandt KD, Kinne RW, Brinkmann O. First-time systematic post-operative clinical assessment of a minimally-invasive approach for lumbar ventrolateral vertebroplasty in the large animal model sheep. Spine J. 2016 Jun 23. pii: S1529-9430(16)30273-X. doi: 10.1016/j.spinee.2016.06.015. [Epub ahead of print]

Charyeva O, Dakischew O, Sommer U, Heiss C, Schnettler R, Lips KS. Biocompatibility of magnesium implants in primary human reaming debris-derived cells stem cells in vitro. J Orthop Traumatol 2016; 17(1):63-73

Cheung WH, Miclau T, Chow SK, Yang FF, Alt V. Fracture healing in osteoporotic bone. Injury 2016 Jun;47 Suppl 2:S21-6

Franke J, Hohendorff B, Alt V, Thormann U, Schnettler R. Suprapatellar nailing of tibial fractures-Indications and technique. Injury 2016 Feb;47(2):495-501

Frerix M, Kröger K, Szalay G, Müller-Ladner U, Tarner IH. Is osteonecrosis of the lunate bone an underestimated feature of systemic sclerosis? A case series of nine patients and review of literature. Semin Arthritis Rheum 2016 Feb;45(4):446-54

Heiß C. Plattensystem LOQTE Q®. Neue Ideen in der winkelstabilen Plattenosteosynthese. JATROS Orthopädie & Traumatologie Rheumatologie 2016; 5:50-53

Hess U, Mikolajczyk G, Treccani L, Streckbein P, Heiss C, Odenbach S, Rezwan K. Multi-loaded ceramic beads/matrix scaffolds obtained by combining ionotropic and freeze gelation for sustained and tuneable vancomycin release. Mater Sci Eng C Mater Biol Appl 2016 Oct 1;67:542-53

Kampschulte M, Krombach GA, Richards DC, Sender J, Lips KS, Thormann U, El Khassawna T, Ray S, Alt V, Langheinrich AC. Neovascularization of osteoporotic metaphyseal bone defects: A morphometric micro-CT study.  Microvasc Res 2016 May;105:7-14

Mika J, Brinkmann O, Clanton TO, Szalay G, Kinne RW. Isolated Acute Exertional Compartment Syndrome (AECS) of the Extensor Carpi Ulnaris. Journal of Orthopaedic Case Reports 2016 Jan-Mar;6(1):5-7

Mohamed W, Domann E, Chakraborty T, Mannala G, Lips KS, Heiss C, Schnettler R, Alt V. TLR9 mediates S. aureus killing inside osteoblasts via induction of oxidative stress. BMC Microbiology 2016, 16:230; DOI: 10.1186/s12866-016-0855-8

Ray S, Khassawna TE, Sommer U, Thormann U, Wijekoon ND, Lips K, Heiss C, Alt V. Differences in expression of Wnt antagonist Dkk1 in healthy versus pathological bone samples. J Microsc 2016 Aug 31. doi: 10.1111/jmi.12469. [Epub ahead of print]

Ray S, Thormann U, Sommer U, Khassawna TE, Hundgeburth M, Henß A, Rohnke M, Lips KS, Heiss C, Heinemann S, Hanke T, Dürselen L, Schnettler R, Alt V. Effects of macroporous, strontium loaded xerogel-scaffolds on new bone formation in critical-size metaphyseal fracture defects in ovariectomized rats. Injury 2016 Jan;47 Suppl 1:S52-61

Roth A, Beckmann J, Bohndorf K, Fischer A, Heiss C, Kenn W, Jäger M, Maus U, Nöth U, Peters KM, Rader C, Reppenhagen S, Smolenski U, Tingart M, Kopp I, Sirotin I, Breusch SJ. S3-Guideline non-traumatic adult femoral head necrosis. Arch Orthop Trauma Surg 2016; 136(2):165-7

Van Lieshout EM, Alt V. Bone graft substitutes and bone morphogenetic proteins for osteoporotic fractures: what is the evidence? Injury 2016 Jan;47 Suppl 1:S43-6

Vehlow D, Schmidt R, Gebert A, Siebert M, Lips KS, Müller M. Polyelectrolyte Complex Based Interfacial Drug Delivery System with Controlled Loading and Improved Release Performance for Bone Therapeutics. Nanomaterials 2016; 6(3), 53

Buchbeiträge und Monographien:

Alt V. Guest Editor Injury 2016; Volume 47 Supplement 1: Osteoporotic fractures – the biological perspective.

Publikationen 2015

Alt V, Franke J, Schnettler R. Local Delivery of Antibiotics in the Surgical Treatment of Bone Infections. Techniques in Orthopaedics 2015 Dec; 30(4):230–235

Alt V, Borgman B, Eicher A, Heiss C, Kanakaris NK, Giannoudis PV, Song F. Effects of recombinant human Bone Morphogenetic Protein-2 (rhBMP-2) in grade III open tibia fractures treated with undreamed nails – A clinical and health economic analysis. Injury 2015; 46(11):2267-72

Bauer NB, Khassawna TE, Goldmann F, Stirn M, Ledieu D, Schlewitz G, Govindarajan P, Zahner D, Weisweiler D, Schliefke N, Böcker W, Schnettler R, Heiss C, Moritz A. Characterization of bone turnover and energy metabolism in a rat model of primary and secondary osteoporosis. Exp Toxicol Pathol 2015 Apr;67(4):287-96

Beckmann J, Schubert J, Morhenn HG, Grau V, Schnettler R, Lips KS. Expression of choline and acetylcholine transporters in synovial tissue and cartilage of patients with rheumatoid arthritis and osteoarthritis. Cell Tissue Res 2015 Feb;359(2):465-77

Blaes F, Dharmalingam B, Tschernatsch M, Feustel A, Fritz T, Kohr D, Singh P, Kaps M, Szalay G. Improvement of complex regional pain syndrome after plasmapheresis. Eur J Pain 2015 Apr;19(4):503-7

Braun T, Kunz U, Schulz C, Lieber A, Willy C. [Near-infrared spectroscopy for the detection of traumatic intracranial hemorrhage : Feasibility study in a German army field hospital in Afghanistan.] Unfallchirurg 2015 Aug;118(8):693-700

Charyeva O, Feyerabend F, Willumeit R, Zukowski D, Gasqueres C, Szakacs G, Ahmad Agha N, Hort N, Gensch F, Cecchinato F, Jimbo R, Wennerberg A, Lips KS. In vitro resorption of magensium materials and ist effect on surface and surrounding environment. MOJ Toxicol 2015;1(1):00004. DOI: 10.15406/mojt.2015.02.00004

Charyeva O, Neilands J, Svensäter G, Wennerberg A. Bacterial biofilm formation on resorbing magnesium implants. Open Journal of Medical Microbiology 2015;5:1-11

Charyeva O, Thormann U, Lips KS, Heimann L, Sommer U, Szalay G, Alt V, Hort N, Schnettler R, Rauschmann M, Schmidt S. Histological Comparison of New Biodegradable Magnesium-Based Implants for Maxillofacial Applications. J Maxillofac Oral Surg 2015 Sep;14(3):637-45

Debus F, Lefering R, Frink M, Kühne CA, Mand C, Bücking B, Ruchholtz S und TraumaRegister DGU. Anzahl der Schwerverletzten in Deutschland. Eine retrospektive Analyse aus dem TraumaRegister der Deutschen Gesellschaft für Unfallchirurgie (DGU). Dtsch Arztebl Int 2015; 112(49): 823-9; DOI: 10.3238/arztebl.2015.0823

El Khassawna T, Böcker W, Brodsky K, Weisweiler D, Govindarajan P, Kampschulte M, Thormann U, Henss A, Rohnke M, Bauer N, Müller R, Deutsch A, Ignatius A, Dürselen L, Langheinrich A, Lips KS, Schnettler R, Heiss C. Impaired extracellular matrix structure resulting from malnutrition in ovariectomized mature rats. Histochem Cell Biol 2015 Nov;144(5):491-507

Haupt M, Kauschke V, Sender J, Kampschulte M, Kovtun A, Dürselen L, Heiss C, Lips KS. Bone status of adult female butyrylcholinesterase gene-deficient mice. Int Immunopharmacol 2015 Nov;29(1):208-14

Heiß C. Defektfüllung bei Osteoporose. Osteologie 2015 Current congress, Berlin, 12.-14. März 2015, S. 6-7

Hess U, Hill S, Treccani L, Streckbein P, Heiss C, Rezwan K. A mild one-pot process for synthesising hydroxyapatite/biomolecule bone scaffolds for sustained and controlled antibiotic release. Biomed Mater 2015; 10(1):015013

Horas K, Schnettler R, Maier G, Schneider G, Horas U. The role of soft-tissue traction forces in bone segment transport for callus distraction : A force measurement cadaver study on eight human femora using a novel intramedullary callus distraction system. Strategies Trauma Limb Reconstr 2015 Apr;10(1):21-6

Jahnke A, Mende JK, Maier GS, Ahmed GA, Ishaque BA, Schmitt H, Rickert M, Clarius M, Seeger JB. Sports activities before and after medial unicompartmental knee arthroplasty using the new Heidelberg Sports Activity Score. Int Orthop 2015 Mar;39(3):449-54

Kampschulte M, Erdmann G, Sender J, Martels G, Böcker W, ElKhassawna T, Heiß C, Langheinrich AC, Roeb E, Roderfeld M. The development and validation of micro‐CT of large deep frozen specimens. Scanning 2015; 37(1):63-72

Kauschke V, Kneffel M, Floel W, Hartmann S, Kampschulte M, Dürselen L, Ignatius A, Schnettler R, Heiss C, Lips KS. Bone status of acetylcholinesterase-knockout mice. Int Immunopharmacol 2015 Nov;29(1):222-30

Lautenschläger S, Striegler C, Dakischew O, Schütz I, Szalay G, Schnettler R, Heiß C, Appelhans D, Lips KS. Effects of dendritic core-shell glycoarchitectures on primary mesenchymal stem cells and osteoblasts obtained from different human donors. J Nanobiotechnology 2015 Oct 8;13(1):65

Lips KS, Kneffel M, Willscheid F, Mathies FM, Kampschulte M, Hartmann S, Panzer I, Dürselen L, Heiss C, Kauschke V. Altered ultrastructure, density and cathepsin K expression in bone of female muscarinic acetylcholine receptor M3 knockout mice. Int Immunopharmacol 2015 Nov;29(1):201-7

Lips KS, Yanko Ö, Kneffel M, Panzer I, Kauschke V, Madzharova M, Henß A, Schmitz P, Rohnke M, Bäuerle T, Liu Y, Kampschulte M, Langheinrich AC, Dürselen L, Ignatius A, Heiss C, Schnettler R, Kilian O. Small changes in bone structure of female alpha7 nicotinic acetylcholine receptor knockout mice. BMC Musculoskelet Disord 2015 Jan 31;16:5

Lorenzetti M, Dakischew O, Trinkaus K, Lips KS, Schnettler R, Kobe S, Novak S., Enhanced osteogenesis on titanium implants by UVB photofunctionalization of hydrothermally grown TiO2 coatings. J Biomater Appl 2015, Vol. 30(1) 71–84

Maier GS, Horas K, Seeger JB, Roth KE, Kurth AA, Maus U. Vitamin D insufficiency in the elderly orthopaedic patient: an epidemic phenomenon. Int Orthop 2015 Apr;39(4):787-92

Maier GS, Seeger JB, Horas K, Roth KE, Kurth AA, Maus U.The prevalence of vitamin D deficiency in patients with vertebral fragility fractures. Bone Joint J 2015 Jan;97-B(1):89-93

Marmor M, Alt V, Latta L, Lane J, Rebolledo B, Egol KA, Miclau T. Osteoporotic Fracture Care: Are We Closer to Gold Standards? J Orthop Trauma 2015 Dec;29 Suppl 12:S53-S56

Maus U, Roth A, Tingart M, Rader C, Jäger M, Nöth U, Reppenhagen S, Heiss C, Beckmann J. S3 Guideline. Part 3: Non-Traumatic Avascular Necrosis in Adults - Surgical Treatment of Atraumatic Avascular Femoral Head Necrosis in Adults. Z Orthop Unfall 2015 Oct;153(5):498-507

Nassenstein C, Wiegand S, Lips KS, Li G, Klein J, Kummer W. Cholinergic activation of the murine trachealis muscle via non-vesicular acetylcholine release involving low-affinity choline transporters. Int Immunopharmacol 2015 Nov;29(1):173-80

Pardun K, Treccani L, Volkmann E, Streckbein P, Heiss C, Li Destri G, Marletta G, Rezwan K. Mixed zirconia calcium phosphate coatings for dental implants: tailoring coating stability and bioactivity potential. Mater Sci Eng C Mater Biol Appl 2015; 48:337-46

Pardun K, Treccani L, Volkmann E, Streckbein P, Heiss C, Gerlach JW, Maendl S, Rezwan K. Magnesium-containing mixed coatings on zirconia for dental implants: mechanical characterization and in vitro behavior. J Biomater Appl 2015 Jul;30(1):104-18

Roth A, Beckmann J, Smolenski U, Fischer A, Jäger M, Tingart M, Rader C, Peters KM, Reppenhagen S, Nöth U, Heiss C, Maus U. S3 guideline. Part 2: Non-Traumatic Avascular Femoral Head Necrosis in Adults - Untreated Course and Conservative Treatment. Z Orthop Unfall 2015 Oct;153(5):488-97

Schlundt C, El Khassawna T, Serra A, Dienelt A, Wendler S, Schell H, van Rooijen N, Radbruch A, Lucius R, Hartmann S, Duda GN, Schmidt-Bleek K. Macrophages in bone fracture healing: Their essential role in endochondral ossification. Bone 2015 Oct 31. pii: S8756-3282(15)00392-0

Sethi S, Thormann U, Sommer U, Stötzel S, Mohamed W, Schnettler R, Domann E, Chakraborty T, Alt V. Impact of prophylactic CpG Oligodeoxynucleotide application on implant-associated Staphylococcus aureus bone infection. Bone 2015; 78:194–202

Striegler C, Schumacher M, Effenberg C, Müller M, Seckinger A, Schnettler R, Voit B, Hose D, Gelinsky M, Appelhans D. Dendritic Glycopolymer as Drug Delivery System for Proteasome Inhibitor Bortezomib in a Calcium Phosphate Bone Cement: First Steps Toward a Local Therapy of Osteolytic Bone Lesions. Macromol Biosci 2015 Sep;15(9):1283-95

Szalay G, Scheufens T, Alt V, Thormann U, Heiss C. Primary results Using the Mini TightRope® for Revision Surgery for Painful Proximalisation of the first Metacarpal after Trapezectomy for CMC-1-osteoarthritis. Handchir Mikrochir Plast Chir 2015 Feb;47(1):17-23

Ternes S, Trinkaus K, Bergen I, Knaack S, Gelinsky M, Kilian O, Heiss C, Lips KS. Impact of acetylcholine and nicotine on human osteoclastogenesis in vitro. Int Immunopharmacol 2015 Nov;29(1):215-21

Thormann U, Alt V, Heimann L, Gasquere C, Heiss C, Szalay G, Franke J, Schnettler R, Lips K. The biocompatibility of degradable magnesium interference screws - An experimental study with sheep. Biomed Res Int 2015;2015:943603

Uhle F, Lichtenstern C, Brenner T, Fleming T, Koch C, Hecker A, Heiss C, Nawroth PP, Hofer S, Weigand MA, Weismüller K. Role of the RAGE Axis during the Immune Response after Severe Trauma: A Prospective Pilot Study. Mediators of Inflammation 2015;Volume 2015, Article ID 691491, 9 pages

Zablotni A, Dakischew O, Trinkaus K, Hartmann S, Szalay G, Heiss C, Lips KS. Regulation of acetylcholine receptors during differentiation of bone mesenchymal stem cells harvested from human reaming debris. Int Immunopharmacol 2015 Nov;29(1):119-26

Buchbeiträge und Monographien:

Schmidt K, Biehl C. Ellenbogen. In: Sell S, Rehart S (Hrsg): Expertise Orthopädische Rheumatologie, S. 243-254, Thieme, 2015, ISBN 978-3131714114

Publikationen 2014

Alt V, Kirchhof K, Seim F, Hrubesch I, Lips KS, Mannel H, Domann E, Schnettler R. Rifampicin-fosfomycin coating for cementless endoprostheses: antimicrobial effects against methicillin-sensitive Staphylococcus aureus (MSSA) and methicillin-resistant Staphylococcus aureus (MRSA). Acta Biomater 2014 Oct;10(10):4518-24

Ambrose CG, Clyburn TA, Mika J, Gogola GR, Kaplan HB, Wanger A, Mikos AG. Evaluation of Antibiotic-Impregnated Microspheres for the Prevention of Implant-Associated Orthopaedic Infections. J Bone Joint Surg Am, 2014 Jan 15;96(2):128 128-134. doi: 10.2106/JBJS.L.01750

Böcker W, El Khassawna T, Bauer N, Brodsky K, Weisweiler D, Govindarajan P, Schlewitz G, Kampschulte M, Dürselen L, Thormann U, Szalay G, Schnettler R, Langheinrich AC, Heiss C. Short-term glucocorticoid treatment causes spinal osteoporosis in ovariectomized rats. Eur Spine J 2014 Nov;23(11):2437-48

Calin M, Helth A, Gutierrez Moreno JJ, Bönisch M, Brackmann V, Giebeler L, Gemming T, Lekka CE, Gebert A, Schnettler R, Eckert J. Elastic softening of β-type Ti-Nb alloys by indium (In) additions. J Mech Behav Biomed Mater 2014 Jul 23;39C:162-174

Cheng C, Alt V, Pan L, Thormann U, Schnettler R, Strauss LG, Schumacher M, Gelinsky M, Dimitrakopoulou-Strauss A. Preliminary evaluation of different biomaterials for defect healing in an experimental osteoporotic rat model with dynamic PET-CT (dPET-CT) using F-18-Sodium Fluoride (NaF). Injury 2014 Mar;45(3):501-5

Cheng C, Alt V, Pan L, Thormann U, Schnettler R, Strauss LG, Heinemann S, Schumacher M, Gelinsky M, Nies B, Dimitrakopoulou-Strauss A. Application of F-18-sodium fluoride (NaF) dynamic PET-CT (dPET-CT) for defect healing: a comparison of biomaterials in an experimental osteoporotic rat model. Med Sci Monit. 2014 Oct 15;20:1942-9

Citak M, Argenson JN, Masri B, Kendoff D, Springer B, Alt V, Baldini A, Cui Q, Deirmengian GK, Del Sel H, Harrer MF, Israelite CL, Jahoda D, Jutte PC, Levicoff E, Meani E, Motta F, Pena OR, Ranawat AS, Safir O, Squire MW, Taunton MJ, Vogely CH, Wellman SS. Spacers. J Arthroplasty 2014 Feb;29(2 Suppl):93-9

Citak M, Argenson JN, Masri B, Kendoff D, Springer B, Alt V, Baldini A, Cui Q, Deirmengian GK, del Sel H, Harrer MF, Israelite C, Jahoda D, Jutte PC, Levicoff E, Meani E, Motta F, Pena OR, Ranawat AS, Safir O, Squire MW, Taunton MJ, Vogely C, Wellman SS. Spacers. J Orthop Res 2014 Jan;32 Suppl 1:S120-9

Fehrendt H, Linn T, Hartmann S, Szalay G, Heiss C, Schnettler R, Lips KS. Negative Influence of a Long-Term High-Fat Diet on Murine Bone Architecture. Int J Endocrinol 2014;2014:318924
http://dx.doi.org/10.1155/2014/318924

Govindarajan P, Böcker W, El Khassawna T, Kampschulte M, Schlewitz G, Huerter B, Sommer U, Dürselen L, Ignatius A, Bauer N, Szalay G, Wenisch S, Lips KS, Schnettler R, Langheinrich A, Heiss C. Bone matrix, cellularity, and structural changes in a rat model with high-turnover osteoporosis induced by combined ovariectomy and a multiple-deficient diet. Am J Pathol 2014 Mar;184(3):765-77

Hak DJ, Fitzpatrick D, Bishop JA, Marsh JL, Tilp S, Schnettler R, Simpson H, Alt V. Delayed union and nonunions: Epidemiology, clinical issues, and financial aspects. Injury. 2014 Jun;45 Suppl 2:S3-7. doi: 10.1016/j.injury.2014.04.002

Kauschke V, Lips KS, Heiss C, Schnettler R. Expression of muscarinic acetylcholine receptors M3 and M5 in osteoporosis. Med Sci Monit 2014 May 27;20:869-74. doi: 10.12659/MSM.890217

Kilian O, Hartmann S, Dongowski N, Karnati S, Baumgart-Vogt E, Härtel FV, Noll T, Schnettler R, Lips KS. BDNF and its TrkB receptor in human fracture healing. Ann Anat 2014 Sep;196(5):286-95. doi: 10.1016/j.aanat.2014.06.001. Epub 2014 Jun 16

Khalil F, Franzmann E, Ramcke J, Dakischew O, Lips KS, Reinhardt A, Heisig P, Maison W. Biomimetic PEG-catecholates for stabile antifouling coatings on metal surfaces: applications on TiO2 and stainless steel. Colloids Surf B Biointerfaces 2014 May 1;117:185-92. doi: 10.1016/j.colsurfb.2014.02.022. Epub 2014 Feb 20

Könnecke I, Serra A, El Khassawna T, Schlundt C, Schell H, Hauser A, Ellinghaus A, Volk HD, Radbruch A, Duda GN, Schmidt-Bleek K. T and B cells participate in bone repair by infiltrating the fracture callus in a two-wave fashion. Bone 2014 Jul;64:155-65

Krämer HH, Hofbauer LC, Szalay G, Breimhorst M, Eberle T, Zieschang K, Rauner M, Schlereth T, Schreckenberger M, Birklein F. Osteoprotegerin - a new biomarker for impaired bone metabolism in complex regional pain syndrome? Pain 2014 Jan 18. pii: S0304-3959(14)00022-0. doi: 10.1016/j.pain.2014.01.014. [Epub ahead of print]

Kühnisch J, Seto J, Lange C, Schrof S, Stumpp S, Kobus K, Grohmann J, Kossler N, Varga P, Osswald M, Emmerich D, Tinschert S, Thielemann F, Duda G, Seifert W, El Khassawna T, Stevenson DA, Elefteriou F, Kornak U, Raum K, Fratzl P, Mundlos S, Kolanczyk M. Multiscale, converging defects of macro-porosity, microstructure and matrix mineralization impact long bone fragility in NF1. PLoS One 2014 Jan 21;9(1):e86115

Lips KS, Kauschke V, Hartmann S, Thormann U, Ray S, Schumacher M, Gelinsky M, Heinemann S, Hanke T, Kautz AR, Schnabelrauch M, Szalay G, Heiss C, Schnettler R, Alt V, Kilian O. Cholinergic nerve fibers in bone defects of a rat osteoporosis model and their regulation by implantation of bone substitution materials. J Musculoskelet Neuronal Interact 2014 Jun;14(2):173-88

Maier GS, Eberhardt C, Strauch M, Kafchitsas K, Kurth AA. Is tartrate-resistant acid phosphatase 5b a potent bio-marker for late stage aseptic implant loosening? Int Orthop 2014 Dec;38(12):2597-600

Maier GS, Horas K, Seeger JB, Roth KE, Kurth AA, Maus U. Is there an association between periprosthetic joint infection and low vitamin D levels? Int Orthop 2014 Jul;38(7):1499-504

Meyer C, Harland U, Kantelberg C, Fischer S, Szalay G. The non-vascularised fibular transfer - indications and limits in infancy and adulthood. Z Orthop Unfall 2014 Dec;152(6):565-71

Meyer C, Szalay G, Alt V, Schnettler R. Triple fracture during rehabilitation after revision total knee arthroplasty. Knee Surg Sports Traumatol Arthrosc 2014 Nov;22(11):2662-4

Mohamed W, Sommer U, Sethi S, Domann E, Thormann U, Schütz I, Lips KS, Chakraborty T, Schnettler R, Alt V. Intracellular proliferation of S. aureus in osteoblasts and effects of rifampicin and gentamicin on S. aureus intracellular proliferation and survival. Eur Cell Mater 2014 Oct 23;28:258-68

Müller R, Kampschulte M, El Khassawna T, Schlewitz G, Hürter B, Böcker W, Bobeth M, Langheinrich AC, Heiss C, Deutsch A. Change of mechanical vertebrae properties due to progressive osteoporosis: combined biomechanical and finite-element analysis within a rat model. Med Biol Eng Comput 2014 Apr;52(4):405-14

Pauksch L, Franke J, Schnettler R, Lips KS. Synergistic toxicity of gentamicin- and nanosilver-doped polymethylmethacrylate bone cement on primary human osteoclasts. Cells Tissues Organs 2014;199(5-6):384-92

Pauksch L, Hartmann S, Rohnke M, Szalay G, Alt V, Schnettler R, Lips KS. Biocompatibility of silver nanoparticles and silver ions in primary human mesenchymal stem cells and osteoblasts. Acta Biomater 2014 Jan;10(1):439-49. doi: 10.1016/j.actbio.2013.09.037. Epub 2013 Oct 3

Pauksch L, Hartmann S, Szalay G, Alt V, Lips KS. In Vitro Assessment of Nanosilver-Functionalized PMMA Bone Cement on Primary Human Mesenchymal Stem Cells and Osteoblasts. PLoS One 2014 Dec 8;9(12):e114740. doi: 10.1371/journal.pone.0114740. eCollection 2014

Roth P, Heiss C,  Koshty A, Niemann B, Boening A. Posttraumatic Arteriovenous Fistula of the Distal Posterior Tibial Artery as Cause of Delayed Wound Healing in an Unrecognized Arterial Injury (OPEN ACCESS). Thorac Cardiovasc Surg Rep 2014;3:67-70

Schwarz EM, Kates SL, Alt V. The 1st International Consensus Meeting on Periprosthetic Joint Infection. J Orthop Res 2014 Jan;32 Suppl 1:S1

Szalay G, Meyer C, Mika J, Schnettler R, Thormann U. Treatment of periprosthetic femoral fractures after total hip arthroplasty with specially constructed retrograde hollow nails. Oper Orthop Traumatol 2014 Dec;26(6):611-24

Szalay G, Scheufens T, Alt V, Boecker W, Schnettler R. Operative treatment of rhizarthrosis with trapezectomy and suspension of the first metacarpal with a Mini TightRope®. Handchir Mikrochir Plast Chir 2014 Jun;46(3):179-85

Thormann U, El Khawassna T, Ray S, Duerselen L, Kampschulte M, Lips K, von Dewitz H, Heinemann S, Heiss C, Szalay G, Langheinrich AC, Ignatius A, Schnettler R, Alt V. Differences of bone healing in metaphyseal defect fractures between osteoporotic and physiological bone in rats. Injury 2014 Mar;45(3):487-93

Uhle F, Nouland Dv, Little S, Menges T, Weiterer S, Szalay G, Franke J, Schnettler R, Weigand MA, Lichtenstern C. Plasmatic isoforms of cytokeratin 18 and RAGE after severe trauma: A longitudinal cohort study. J Trauma Acute Care Surg 2014 Oct;77(4):577-84

Publikationen 2013

Alt V, Thormann U, Ray S, Zahner D, Dürselen L, Lips K, El Khassawna T, Heiss C, Riedrich A, Schlewitz G, Ignatius A, Kampschulte M, von Dewitz H, Heinemann S, Schnettler R, Langheinrich A. A new metaphyseal bone defect model in osteoporotic rats to study biomaterials for the enhancement of bone healing in osteoporotic fractures. Acta Biomater 2013 Jun;9(6):7035-42

Beckmann J, Lips KS. The non-neuronal cholinergic system in health and disease. Pharmacology 2013;92(5-6):286-302. doi: 10.1159/000355835. Epub 2013 Nov 29

Cheng C, Alt V, Dimitrakopoulou-Strauss A, Pan L, Thormann U, Schnettler R, Weber K, Strauss LG. Evaluation of new bone formation in normal and osteoporotic rats with a 3-mm femur defect: functional assessment with dynamic PET-CT (dPET-CT) using 2-deoxy-2-[(18)F]fluoro-D-glucose ( (18)F-FDG) and (18)F-fluoride. Mol Imaging Biol 2013 Jun;15(3):336-44

Cheng C, Heiss C, Dimitrakopoulou-Strauss A, Govindarajan P, Schlewitz G, Pan L, Schnettler R, Weber K, Strauss LG. Evaluation of bone remodeling with (18)F-fluoride and correlation with the glucose metabolism measured by (18)F-FDG in lumbar spine with time in an experimental nude rat model with osteoporosis using dynamic PET-CT. Am J Nucl Med Mol Imaging 2013;3(2):118-28. Epub 2013 Mar 8

Elkhassawna T, Böcker W, Govindarajan P, Schliefke N, Hürter B, Kampschulte M, Schlewitz G, Alt V, Lips KS, Faulenbach M, Möllmann H, Zahner D, Dürselen L, Ignatius A, Bauer N, Wenisch S, Langheinrich AC, Schnettler R, Heiss C. Effects of Multi-Deficiencies-Diet on Bone Parameters of Peripheral Bone in Ovariectomized Mature Rat. PLOS ONE 2013 Aug; 8(8), e71665:1-12

Goergen J, Wenisch S, Raabe O, Moritz A, Schlewitz G, Schnettler R, Hempel U, Heiss C, Arnhold S. Characterization of Bone-Marrow-Derived Stem Cells in Osteoporotic Models of the Rat. ISRN Stem Cells 2013; Volume 2013, Article ID 262451, 9 pages, http://dx.doi.org/10.1155/2013/262451

Govindarajan P, ElKhassawna T, Kampschulte M, Böcker W, Huerter B, Dürselen L, Faulenbach M, Heiss C. Implications of combined ovariectomy and glucocorticoid (dexamethasone) treatment on mineral, microarchitectureal, biomechanical and matrix properties of rat bone. Int J Exp Pathol 2013 [Epub ahead of print]

Govindarajan P, Schlewitz G, Schliefke N, Weisweiler D, Alt V, Thormann U, Lips KS, Wenisch S, Langheinrich AC, Zahner D, Hemdan NY, Böcker W, Schnettler R, Heiss C. Implications of combined Ovariectomy/Multi-Deficiency Diet on rat bone with age-related variation in Bone Parameters and Bone Loss at Multiple Skeletal Sites by DEXA. Med Sci Monit Basic Res 2013 Feb 28;19:76-86

Grüner D, Lips KS, Heiss C, Schnettler R, Kollmann T, Simon P, Kniep R. Irregular Shaped, Assumably Semi-Crystalline Calciumphosphate Platelet Deposition at the Mineralization Front of Rabbit Femur Osteotomy: A HR-TEM Study. Scanning 2013 May;35(3):169-82

Heinemann S, Heinemann C, Wenisch S, Alt V, Worch H, Hanke T. Calcium phosphate phases integrated in silica/collagen nanocomposite xerogels enhance the bioactivity and ultimately manipulate the osteoblast/osteoclast ratio in a human co-culture model. Acta Biomater 2013 Jan; 9(1):4878-88

Heiss C, Maier G, Gelinsky M, Hose D, Schnettler R. Klinische Verwendung osteologischer Biomaterialien. Osteologie 2013; 3: 173-178

Henss A, Rohnke M, ElKhassawna T, Govindarajan P, Schlewitz G, Heiss C, Janek J. Applicability of ToF-SIMS for monitoring compositional changes in bone in a long term animal model. J R Soc Interface 2013; 10: 20130332

Kraus R, Stahl JP, Heiss C, Horas U, Dongowski N, Schnettler R. Fractures of the thoracic and lumbar spine in children and adolescents. Unfallchirurg 2013 May;116(5):435-41

Lips KS, Kauschke V, Hartmann S, Thormann U, Ray S, Kampschulte M, Langheinrich A, Schumacher M, Gelinsky M, Heinemann S, Hanke T, Kautz AR, Schnabelrauch M, Schnettler R, Heiss C, Alt V, Kilian O. Podoplanin immunopositive lymphatic vessels at the implant interface in a rat model of osteoporotic fractures. PLoS One 2013 Oct 9;8(10):e77259. doi: 10.1371/journal.pone.0077259

Liu Y, Cao L, Ray S, Thormann U, Hillengass J, Delorme S, Schnettler R, Alt V, Bäuerle T. Osteoporosis influences osteogenic but not angiogenic response during bone defect healing in a rat model. Injury 2013 Jul;44(7):923-9. Epub 2013 Mar 20

Liu Y, Cao L, Hillengass J, Delorme S, Schlewitz G, Govindarajan P, Schnettler R, Heiß C, Bäuerle T. Quantitative assessment of microcirculation and diffusion in the bone marrow of osteoporotic rats using VCT, DCE-MRI, DW-MRI, and histology. Acta Radiol 2013 Mar 1; 54(2):205-13. Epub 2013 Jan 14

Maier GS, Jakobs P, Roth KE, Kurth AA, Maus U. Is there an epidemic vitamin D deficiency in german orthopaedic patients? Clin Orthop Relat Res 2013 Sep;471(9):3029-35. doi: 10.1007/s11999-013-2996-5. Epub 2013 Apr 23

Maier GS, Jakobs P, Horas K, Roth KE, Kurth AA, Maus U. Vitamin D deficiency in orthopaedic patients- a single center analysis. Acta Orthop Belg 2013 Oct;79(5):587-91

Maier GS, Percic D, Maus U, Kurth AA. Mastocytosis-induced osteoporosis - rare but severe. Osteology/Osteologie 2013;22(2):136-139

Meyer C, Szalay G, Alt V, Schnettler R. Triple fracture during rehabilitation after revision total knee arthroplasty. Knee Surg Sports Traumatol Arthrosc 2013 May 29. [Epub ahead of print]

Nandigama R, Ibañez-Tallon I, Lips KS, Schwantes U, Kummer W, Bschleipfer T. Expression of nicotinic acetylcholine receptor subunit mRNA in mouse bladder afferent neurons. Neuroscience 2013 Jan 15;229:27-35. doi: 10.1016/j.neuroscience.2012.10.059. Epub 2012 Nov 3

Pardun K, Treccani L, Volkmann E, Li Destri G, Marletta G, Streckbein P, Heiss C, Rezwan K. Characterization of Wet Powder-Sprayed Zirconia/Calcium Phosphate Coating for Dental Implants. Clin Implant Dent Relat Res 2013 Apr 9. doi: 10.1111/cid.12071. [Epub ahead of print]

Pauksch L, Hartmann S, Szalay G, Alt V, Schnettler R, Lips KS. Biocompatibility of an antibacterial nanosilver-coated titanium implant on primary human mesenchymal stem cells and osteoblasts. Int J Biol Med Res 2013; 4(4): 3179-3726

Rohnke M, Henss A, Kokesch-Himmelreich J, Schumacher M, Ray S, Alt V, Gelinsky M, Janek J. Mass spectrometric monitoring of Sr-enriched bone cements--from in vitro to in vivo. Anal Bioanal Chem 2013 Nov;405(27):8769-80

Ruesseler M, Schill A, Stibane T, Damanakis A, Schleicher I, Menzler S, Braunbeck A, Walcher F. Practical clinical competence" - a joint programme to improve training in surgery. Zentralbl Chir 2013 Dec;138(6):663-8. doi: 10.1055/s-0032-1328180. Epub 2013 Apr 10 [Article in German]

Schleicher I, Lips KS, Sommer U, Schappat I, Martin AP, Szalay G, Hartmann S, Schnettler R. Biphasic scaffolds for repair of deep osteochondral defects in a sheep model. J Surg Res 2013 Jul;183(1):184-92

Schleicher I, Lips KS, Sommer U, Schappat I, Martin AP, Szalay G, Schnettler R. Allogenous bone with collagen for repair of deep osteochondral defects. J Surg Res 2013 Dec;185(2):667-75. doi: 10.1016/j.jss.2013.07.061. Epub 2013 Sep 21

Schlewitz G, Govindarajan P, Schliefke N, Alt V, Böcker W, Elkhassawna T, Thormann U, Lips KS, Hemdan NY, Zahner D, Schnettler R, Heiss C. Ovariectomy and calcium/vitamin d2/d3 deficient diet as a model of osteoporosis in the spine of sprague-dawley rats. Z Orthop Unfall 2013 Feb;151(1):14-9

Szalay G, Meyer C, Thormann U, Alt V, Schnettler R. The Operative Treatment of a Bowstring Phenomenon of the Thumb in Childhood: Case Report and Literature Review. Handchir Mikrochir Plast Chir 2013 Oct;45(5):293-296. Epub 2013 Oct 2. German

Szalay G, Meyer C, Scheufens T, Schnettler R, Christ R, Schleicher I. Pyrocarbon spacer as a trapezium replacement for arthritis of the trapeziometacarpal joint: A follow-up study of 60 cases. Acta Orthop Belg 2013; 79(6): 648-654

Szalay G, Thormann U, Boecker W, Schleicher I, Schnettler R. Reconstruction of a Broad Infected Defect Zone of the Distal Part of the Radius by Tractionosteogenesis. Handchir Mikrochir Plast Chir 2013 Oct; 45(5):306-310. Epub 2013 Oct 2. German

Thormann U, Erli HJ, Brügmann M, Szalay G, Schlewitz G, Pape HC, Schnettler R, Alt V. Association of clinical parameters of operatively treated thoracolumbar fractures with quality of life parameters. Eur Spine J 2013 May 7. [Epub ahead of print]

Thormann U, Ray S, Sommer U, Elkhassawna T, Rehling T, Hundgeburth M, Henß A, Rohnke M, Janek J, Lips KS, Heiss C, Schlewitz G, Szalay G, Schumacher M, Gelinsky M, Schnettler R, Alt V. Bone formation induced by strontium modified calcium phosphate cement in critical-size metaphyseal fracture defects in ovariectomized rats. Biomaterials 2013 Nov;34(34):8589-98. doi: 10.1016/j.biomaterials.2013.07.036. Epub 2013 Jul 29

Thormann U, Ray S, Sommer U, El Khassawna T, Heiss C, Schnettler R, Alt V. Biomaterials for enhancement of bone healing in osteoporotic fractures. BioNanoMaterials 2013;14: Heft 3-4: 135-142

Buchbeiträge und Monographien:

Heiss C, Alt V, Schnettler R. Weißbuch Forschung in Orthopädie & Unfallchirurgie, Kapitel 5.d: Zukunftsperspektiven muskuloskelettaler Forschung: Grundlagenforschung, Regenerative Biomaterialien. Shaker Verlag GmbH 2013, S. 114-116, ISBN 978-3-8440-1775-5

Mika J, Krueger GRF. Pathology of Bones and Soft Tissues. In: Atlas of Anatomic Pathology with Imaging. A Correlative Diagnostic Companion (edited by: Krueger GRF, Buja LM, Chandrasekhar C). Springer London Ltd. 2013. ISBN-10: 1447128451, ISBN-13: 978-1447128458

Publikationen 2012

Arabmotlagh M, Sommer U, Dingeldein E, Rauschmann M, Schnettler R. Nanocrystalline hydroxyapatite facilitates bone apposition to polymethylmethacrylate: Histological investigation using a sheep model.J Orthop Res 2012 Aug;30(8):1290-5

Bschleipfer T, Weidner W, Kummer W, Lips KS. Does bladder outlet obstruction alter the non-neuronal cholinergic system of the human urothelium? Life Sci 2012; 91(21-22):1082-6

Heiss C, Govindarajan P, Schlewitz G, Hemdan NY, Schliefke N, Alt V, Thormann U, Lips KS, Wenisch S, Langheinrich AC, Zahner D, Schnettler R. Induction of osteoporosis with its influence on osteoporotic determinants and their interrelationships in rats by DEXA. Med Sci Monit 2012 Jun 1;18(6):BR199-207

Hollenhorst MI, Lips KS, Kummer W, Fronius M. Nicotine-induced activation of soluble adenylyl cyclase participates in ion transport regulation in mouse tracheal epithelium. Life Sci 2012; 91:1009–1012

Hollenhorst MI, Lips KS, Wolff M, Wess J, Gerbig S, Takats Z, Kummer W, Fronius M. Luminal cholinergic signalling in airway lining fluid: a novel mechanism for activating chloride secretion via Ca2+-dependent Cl- and K+ channels. Br J Pharmacol 2012 Jun;166(4):1388-402

Hollenhorst MI, Lips KS, Weitz A, Krasteva G, Kummer W, Fronius M. Evidence for functional atypical nicotinic receptors that activate K+-dependent Cl- secretion in mouse tracheal epithelium. Am J Respir Cell Mol Biol 2012 Jan;46(1):106-14

Kliemann K, Kneffel M, Bergen I, Kampschulte M, Langheinrich AC, Dürselen L, Ignatius A, Kilian O, Schnettler R, Lips KS. Quantitative analyses of bone composition in acetylcholine receptor M3R and alpha7 knockout mice. Life Sci 2012; 91(21-22): 997-1002

Kraus R, Albrecht J, Schnettler R, von Pichler M. Reconstruction of the heel in a two-year-old boy after lawn mower injury. Z Orthop Unfall 2012 Apr;150(2):177-80

Kraus R, Alzen G, Dreyer T, Szalay G, Schnettler R. Dupuytren's Disease in Children - Case Report and Literature Review. Handchir Mikrochir Plast Chir 2012 Jun;44(3):175-7. Epub 2012 Jul 25

Liu Y, Bäuerle T, Pan L, Dimitrakopoulou-Strauss A, Strauss LG, Heiss C, Schnettler R, Semmler W, Cao L. Calibration of Cone Beam CT using Relative Attenuation Ratio for Quantitative Assessment of Bone Density: A Small Animal Study. Int J Comput Assist Radiol Surg 2012 Dec 8. [Epub ahead of print]

Meyer C, Kantelberg C, Szalay G, Alt V, Schnettler R. Periprothetische Femurfraktur nach Knietotalendoprothese. Trauma Berufskrankh 2012; 14 [Suppl 3]:331–334. DOI 10.1007/s10039-012-1846-0

Mika J, Schleicher I, Gerlach U, Adler CP, Uhl M, Knoeller SM. Primary Bone Lymphomas Thought to Be Osteomyelitis Urgently Demand a Rapid Diagnosis in Bone Pathology. Anticancer Res 2012;32(11):4905-4912

Paddenberg R, Tiefenbach M, Faulhammer P, Goldenberg A, Gries B, Pfeil U, Lips KS, Piruat JI, López-Barneo J, Schermuly RT, Weissmann N, Kummer W. Mitochondrial complex II is essential for hypoxia-induced pulmonary vasoconstriction of intra- but not of pre-acinar arteries. Cardiovasc Res 2012;  93(4):702-10

Schleicher I, Haselbacher M, Mayr E, Kaiser PM, Lenze FW, Keiler A, Nogler M. Accuracy of navigation in hip resurfacing with different surgeons and varying anatomy. Comput Aided Surg 2012; 17(2):77-85

Schleicher I, Lappas K, Klein H, Szalay G, Kordelle J. Follow up of complete subtalar release for clubfoot-Evolution of different scores. Foot Ankle Surg 2012 Mar;18(1):55-61. Epub 2011 Apr 13

Schleicher I, Lips KS, Sommer U, Schappat I, Martin AP, Szalay G, Hartmann S, Schnettler R. Biphasic scaffolds for repair of deep osteochondral defects in a sheep model. J Surg Res 2012 Dec 7. [Epub ahead of print]

Schlewitz G, Govindarajan P, Schliefke N, Böcker W, el Khassawna T,  Alt V, Thormann U,  Lips KS, Hemdan NY,  Zahner D, Schnettler R, Heiss C. Ovariectomy and calcium-/vitamin D2/3-deficient diet as a model of osteoporosis in the spine of sprague-dawley rats. Z Orthop Unfall 2012 (accepted)

Schubert J, Beckmann J, Hartmann S, Morhenn HG, Szalay G, Heiss C, Schnettler R, Lips KS. Expression of the non-neuronal cholinergic system in human knee synovial tissue from patients with rheumatoid arthritis and osteoarthritis. Life Sci 2012; 91(21-22):1048-52

Seckinger A, Meiβner T, Moreaux J, Depeweg D, Hillengass J, Hose K, Rème T, Rösen-Wolff A, Jauch A, Schnettler R, Ewerbeck V, Goldschmidt H, Klein B, Hose D. Clinical and prognostic role of annexin A2 in multiple myeloma. Blood 2012 Aug 2;120(5):1087-94. Epub 2012 Jun 15

Szalay G, Stigler B, Kraus R, Böhringer G, Schnettler R. Proximal Row Carpectomy and Replacement of the Proximal Pole of the Capitate by Means of a Pyrocarbon Cap (RCPI) in Advanced Carpal Collapse. Handchir Mikrochir Plast Chir 2012 Jan;44(1):17-22. doi: 10.1055/s-0031-1284335. Epub 2011 Aug 25

Weiterer S, Trierweiler-Hauke B, Hecker A, Szalay G, Heinrich M, Mayer K, Weigand MA. Frühmobilisation des chirurgischen Intensivpatienten. Intensivmedizin up2date 2012, 8:165-180

Wenisch S, Cavalcanti-Adam EA, Tryankowski E, Raabe O, Kilian O, Heiss C, Alt V, Arnhold S, Schnettler R. Light- and transmission-electron-microscopic investigations on distribution of CD44, connexin 43 and actin cytoskeleton during the foreign body reaction to a nanoparticular hydroxyapatite in mini-pigs. Acta Biomater 2012; 8: 2807–2814. Epub 2012 Mar 30

Wolff M, Noreikat K, Ibanez-Tallon I, Lips KS, Kölle S, Kummer W. Cholinergic receptors in the murine oviduct: inventory and coupling to intracellular calcium concentration. Life Sci 2012; 91(21-22):1003-8

Buchbeiträge und Monographien:

Schleicher I, Kilian O, Schnettler R. Die primäre Endoprothetik des Hüftgelenkes.  In: Endoprothetik – ein Leitfaden für Praktiker, 3. Auflage, Herausgeber Krukemeyer MG, Möllenhoff G, DE GRUYTER Verlag 2012; Kapitel 6, S. 99-128, ISBN 978-3-11-028699-1 

Schnettler R, Steinau H.-S. Infected Bone and Joint Surgery treatment (Chinese Edition). People's Health Publishing House 2012, ISBN 978-7-117-15871-8, 245 Seiten

Schnettler R, Steinau H.-S. Leczenie chirurgiczne w zapaleniach kości i stawów. Med-Media, Warszawa 2012, ISBN 978-83-62875-09-2, 313 Seiten

Publikationen 2011

Alt V, Kögelmaier D, Lips KS, Witt V, Pacholke S, Heiss C, Kampschulte M, Heinemann S, Hanke T, Thormann U, Schnettler R, Langheinrich AC. Assessment of angiogenesis in osseointegration of a silica-collagen biomaterial using three-dimensional nano-computed tomography. Acta Biomater 2011 Oct; 7(10): 3773-9. Epub 2011 Jun 23

Alt V, Bitschnau A, Böhner F, Heerich KE, Magesin E, Sewing A, Pavlidis T, Szalay G, Heiss C, Thormann U, Hartmann S, Pabst W, Wenisch S, Schnettler R. Effects of gentamicin and gentamicin-RGD coatings on bone ingrowth and biocompatibility of cementless joint prostheses: an experimental study in rabbits. Acta Biomater 2011 Mar;7(3):1274-80

Alt V, Lips KS, Henkenbehrens C, Muhrer D, Cavalcanti-Garcia M, Sommer U, Thormann U, Szalay G, Heiss C, Pavlidis T, Domann E, Schnettler R. A new animal model for implant-related infected non-unions after intramedullary fixation of the tibia in rats with fluorescent in situ hybridization of bacteria in bone infection. Bone 2011 May 1;48(5):1146-53. Epub 2011 Jan 28

Hackethal A, Sick C, Szalay G, Puntambekar S, Joseph K, Langde S, Oehmke F, Tinneberg HR, Muenstedt K. Intra-abdominal adhesion formation: Does surgical approach matter? Questionnaire survey of South Asian surgeons and literature review. J Obstet Gynaecol Res 2011 Oct;37(10):1382-90

Henß A, Rohnke M, Janek J, Heiß C. Morschen Knochen auf der Spur. Labor&more  2011; 4: 2-7

Horas U, Meissner SA, Kraus R, Heiss C, Schnettler R.  Effect of malpositioned anterior cruciate ligament replacement on knee joint structures: a biomechanical model.  Biomed Tech (Berl) 2011; 56(6):321-5. Epub 2011 Nov 23

Kaiser MM, Wessel LM, Kraus R, Rapp M. Alte und neue Konzepte in der Kindertraumatologie – Abschied von der Extensionsbehandlung. Praktische Pädiatrie 2011; 17: 98-108

Kraus R, Herbst U, Perler G, Schnettler R, Röder C. Traumatic physeal separations of the distal tibia. Occurrence, forms, treatment strategies. Unfallchirurg 2011 May;114(5):403-10

Kraus R, Horas U, Szalay G, Alt V, Kaiser M, Schnettler R. School-related injuries: a retrospective 5-year evaluation. Eur J Trauma Emerg Surg 2011; 4:411-418

Kraus R, Peters F, Geck A, Lips KS, Obert M, Röder C, Schnabelrauch M, Schnettler R, Heiss C. Adhesive Strength of a β-Tricalcium Phosphate-Enriched Bone Adhesive. Z Orthop Unfall 2011 Jun;149(3):271-278

Kraus R, Reyers J, Alt V, Schnettler R, Berthold LD. Physiological closure of the physeal plate of the distal radius: An MRI analysis. Clin Anat 2011 Nov; 24(8): 1010-5. doi: 10.1002/ca.21199

Kraus R, Röder C, Perler G, Schneidmüller D, Sommerfeldt D, Wessel L, Schnettler R, Linhart W: Do Paediatric and Adult Surgeons Follow Different Approaches to Physeal Fractures? Zentralbl Chir 2011 Apr;136(2):164-7

Meyer C, Alt V, Heiss C, Kraus R, Szalay G, Schnettler R. Intramedullary nailing of periprosthetic femoral fractures after revision for total knee endoprosthesis: Treatment of periprosthetic femoral fractures by inserted knee endoprosthesis with intramedullary shaft by in situ lengthening of the prosthesis with specially prepared slotted hollow nails. Unfallchirurg 2011 Mar;114(3):241-7

Offer L, Veigel B, Pavlidis T, Heiss C, Gelinsky M, Reinstorf A, Wenisch S, Lips KS, Schnettler R. Phosphoserine-modified calcium phosphate cements: bioresorption and substitution. J Tissue Eng Regen Med 2011 Jan;5(1):11-9. doi: 10.1002/term.283

Schirmer SU, Eckhardt I, Lau H, Klein J, Degraaf YC, Lips KS, Pineau C, Gibbins IL, Kummer W, Meinhardt A, Haberberger RV. The cholinergic system in rat testis is of non-neuronal origin. Reproduction 2011 Jul;142(1):157-166. Epub 2011 Apr 11

Schleicher I, Haas H, Adams TS, Szalay G, Klein H, Kordelle J. Minimal-invasive posterior approach for total hip arthroplasty versus standard lateral approach. Acta Orthop Belg 2011 Aug;77(4):480-7

Schneidmüller D, Röder C, Kraus R, Marzi I, Kaiser M, Dietrich D, von Laer L. Development and validation of a paediatric long-bone fracture classification. A prospective multicentre study in 13 European paediatric trauma centres. BMC Musculoskelet Disord 2011 May;12:89

Szalay G, Schleicher I, Alt V, Pavlidis T, Schnettler R. Operative treatment of rhizarthritis : Comparison of ligament reconstruction according to Epping with trapezectomy and interposition of pyrocarbon spacers as replacement of the trapezium. Orthopade 2011 Mar;40(3):237-246

Szalay G, Schleicher I, Kraus R, Pavlidis T, Schnettler R. Operative Treatment of the Mallet Fracture using a Hook Plate. Handchir Mikrochir Plast Chir 2011 Feb;43(1):46-53

Hackethal A, Sick C, Szalay G, Puntambekar S, Joseph K, Langde S, Oehmke F, Tinneberg HR, Muenstedt K. Intra-abdominal adhesion formation: Does surgical approach matter? Questionnaire survey of South Asian surgeons and literature review. J Obstet Gynaecol Res 2011. doi:10.1111/j.1447-0756.2011.01543.x

Szalay G, Schleicher I, Schiefer UR, Alt V, Schnettler R. Operative treatment of osseous pull out of the extensor tendon using a hook plate. Oper Orthop Traumatol 2011 Apr;23(2):151-7. doi: 10.1007/s00064-010-0008-4

Buchbeiträge und Monographien:

Kilian O, Schnettler R. Primäre Endoprothetik des Hüftgelenkes. In: Endoprothetik: Ein Leitfaden für den Praktiker. Krukemeyer MG, Möllenhoff G. (Hrsg.); 2. Auflage, De Gruyter Verlag 2011; Kapitel 4, S. 63-88, ISBN 978-3-11-028018-0

Kraus R. Untersuchungen zur Biokompatibilität und Biomechanik eines beta-Tricalcium-phosphat angereicherten Knochenklebstoffs. Shaker Verlag Aachen, 2011, 256 Seiten, ISBN 978-3-8322-9878-4

Schnettler R, Steinau H.-U. Cirugía del Hueso y la Articulacion Septicos. AMOLCA, 2011, 316 págs, ISBN 978-958-755-032-0

Alt V, Schnettler R. Antecedentes historicos. In: Schnettler R, Steinau H.-U. Cirugía del Hueso y la Articulacion Septicos. AMOLCA (2011), Kapitel 1, S. 1-3, ISBN 978-958-755-032-0

Kraus R, Schiefer U, Schnettler R. Tratamiento quirúrgico local de la osteomielitis con un portador de antibiótico reabsorbible y osteoconductivo. In: Schnettler R, Steinau H.-U. Cirugía del Hueso y la Articulacion Septicos. AMOLCA (2011), Kapitel 5, S. 126-132, ISBN 978-958-755-032-0

Schnettler R, Alt V. Fisiopatología y clasificación de la osteomielitis. In: Schnettler R, Steinau H.-U. Cirugía del Hueso y la Articulacion Septicos. AMOLCA (2011), Kapitel 2, S. 5-14, ISBN 978-958-755-032-0

Schnettler R. Osteomielitis postraumática aguda y crónica. In: Schnettler R, Steinau H.-U. Cirugía del Hueso y la Articulacion Septicos. AMOLCA (2011), Kapitel 5, S. 94-125, ISBN 978-958-755-032-0

von Laer L, Linhart W, Kraus R. Kommunikation in der Kindertraumatologie. In: Hax, Hax-Schoppenhorst (Hrsg.): Kommunikation mit Patienten der Chirurgie. Kohlhammer 2011, 194-202

Publikationen 2010

Garrison KR, Shemilt I, Donell S, Ryder JJ, Mugford M, Harvey I, Song F, Alt V. Bone morphogenetic protein (BMP) for fracture healing in adults. Cochrane Database Syst Rev 2010 Jun 16;6:CD006950. Review

Heiss C, Schettler N, Wenisch S, Cords S, Schilke F, Lips KS, Alt V, Schnettler R. Bond strength of an alkylene bis(dilactoyl)-methacrylate bone adhesive: a biomechanical evaluation in sheep. J Biomater Sci Polym Ed 2010; 21(10): 1345-58. Epub 2010 Jun 8.

Horas U, Meissner SA, Heiss C, Schnettler R. Arthroscopic fixation of posterior cruciate ligament avulsion fractures: a new minimally invasive technique. Knee Surg Sports Traumatol Arthrosc 2010 Jun;18(6): 781-3. Epub 2009 Oct 14

Khalipour P, Lampe K, Wagener M, Stigler B, Heiss C, Ullrich MS, Domann E, Schnettler R, Alt V. Ag/SiO(x)C(y) plasma polymer coating for antimicrobial protection of fracture fixation devices. J Biomed Mater Res B Appl Biomater 2010 Jul;94(1): 196-202

Kraus R. Kinder- und Jugendtraumatologie: Behandlungsstrategien bei proximalen Radiusfrakturen. Orthopädie und Rheuma 2010; 13: 34-37

Kraus R. Klassifikation von Frakturen im Wachstumsalter. OP Journal 2010; 26: 70-77

Kraus R, Dongowski N, Szalay G, Schnettler R. Missed elbow fractures misdiagnosed as radial head subluxations. Acta Orthop Belg 2010 Jun;76(3): 312-5

Kraus R, Schnettler R: Gutachten nach Osteitis. Unfallmedizinische Schriften der Landesverbände der gewerblichen Berufsgenossenschaften 2010; 108:85-93

Kraus R, Pavlidis T, Dongowski N, Szalay G, Schnettler R. Children and adolescents with posttraumatic shoulder instability benefit from arthroscopic stabilization. Eur J Pediatr Surg 2010 Jul;20(4): 253-6. Epub 2010 Apr 9.

Kraus R, Pavlidis T, Heiss C, Kilian O, Schnettler R. Arthroscopic treatment of post-traumatic shoulder instability in children and adolescents. Knee Surg Sports Traumatol Arthrosc 2010 Dec;18(12):1738-41. Epub 2010 Mar 9

Kraus R, Wessel L. The treatment of upper limb fractures in children and adolescents. Dtsch Arztebl Int 2010 Dec;107(51-52):903-10. Epub 2010 Dec 27

Mann V, Mann S, Szalay G, Hirschburger M, Röhrig R, Dictus C, Wurmb T, Weigand MA, Bernhard M. Treatment of polytrauma in the intensive care unit. Anaesthesist 2010 Aug;59(8):739-61; quiz 762-3

Mikulski Z, Hartmann P, Jositsch G, Zasłona Z, Lips KS, Pfeil U, Kurzen H, Lohmeyer J, Clauss WG, Grau V, Fronius M, Kummer W. Nicotinic receptors on rat alveolar macrophages dampen ATP-induced increase in cytosolic calcium concentration. Respir Res 2010 Sep 29;11:133 

Prinz KS, Rapp M, Kraus R, Wessel, LM, Kaiser MM. Dislozierte Klavikulafrakturen im Kindes- und Jugendalter: Wer profitiert von einer Operation? Z Orthop Unfall 2010; 148: 60-65

Schleicher I, Szalay G, Kordelle J. Treatment of epicondylitis - a current review. Sportverletz Sportschaden 2010 Dec;24(4):218-24

Szalay G, Meyer C, Alt V, Heiss C, Schnettler R, Hackethal A: Acute compartment syndrome of the lower leg as interdisciplinary complication after long duration intervention in the lithotomy position. Zentralbl Chir 2010 Apr;135(2): 163-7. Epub 2010 Apr 8

Szalay G, Schleicher I, Kraus R, Stigler B, Schnettler R: The Operative Treatment of the Dorsal Distal Phalanx near to the Base (Osseous Pull out of the Extensor Tendon) with Extreme Exposure of the Hand by Athletic Activies – Is the Hook Plate an Option for Treatment? Sportverletz Sportschaden 2010 Sep;24(3): 159-165. Epub 2010 Sep 15

Buchbeiträge und Monographien:

Kraus R. Epidemiologie. In: Marzi I (Hrsg.): Kindertraumatologie, Springer Verlag Heidelberg, 2. überarbeitete Auflage, 2010; 31-35, ISBN 978-3-642-00989-1

Schnettler R, Steinau H.-U. (Editors). Septic Bone and Joint Surgery. Thieme Verlag Stuttgart 2010, ISBN 978-3-13-149031-5

Alt V, Schnettler R. Historical Background. In: Schnettler R, Steinau H.-U. (Editors). Septic Bone and Joint Surgery. Thieme, Stuttgart (2010), ISBN 978-3-13-149031-5, S. 1-3

Kraus R, Schiefer U, Schnettler R. Local Surgical Treatment of Osteomyelitis with a Resorbable, Osteoconductive Antibiotic Carrier. In: Schnettler R, Steinau H.-U. (Editors). Septic Bone and Joint Surgery. Thieme, Stuttgart (2010), ISBN 978-3-13-149031-5, S. 126-132

Schnettler R, Alt V. Pathophysiology and Classification of Osteomyelitis. In: Schnettler R, Steinau H.-U. (Editors). Septic Bone and Joint Surgery. Thieme, Stuttgart (2010), ISBN 978-3-13-149031-5, S. 5-14

Schnettler R. Acute and Chronic Post-traumatic Osteomyelitis. In: Schnettler R, Steinau H.-U. (Editors). Septic Bone and Joint Surgery. Thieme, Stuttgart (2010), ISBN 978-3-13-149031-5, S. 94-125